Biotech Nephrogen combines AI and gene therapy to reverse kidney disease — check it out at TechCrunch Disrupt 2025 | TechCrunch

Biotech Nephrogen: Reversing Kidney Disease with AI and Gene Therapy

Demetri Maxim's life was impacted by kidney disease at a young age, when his mother's kidneys stopped working and she had to undergo dialysis.

Maxim's mother later received a kidney transplant, but he inherited Polycystic Kidney Disease (PKD) from her. About 1 in 7 Americans has Chronic Kidney Disease (CKD), with 10% of cases due to genetic conditions.

Maxim became determined to find a cure, and his "Aha!" moment came in 2021 when Nature Magazine published a study showing that PKD is reversible in mice using CRISPR technology.

PKD is reversible in mice using CRISPR technology.

Author's summary: Biotech Nephrogen uses AI and gene therapy to reverse kidney disease.

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TechCrunch TechCrunch — 2025-10-27