GLP-1 Drugs and Weight Loss
Three new Cochrane reviews find evidence that GLP-1 drugs result in clinically meaningful weight loss.
The reviews, commissioned by the World Health Organization (WHO), examine the effects of three weight loss drugs known as GLP-1 receptor agonists.
- All three drugs result in clinically meaningful weight loss compared with placebo.
- Evidence on longer-term outcomes, side effects, and potential conflicts of interest remains limited or uncertain.
Industry-funded studies raise questions.
The reviews aim to inform upcoming guidelines on the use of these drugs to treat obesity.
Author's summary: GLP-1 drugs aid weight loss.